N2 News

Conserve 2021 Statement Published

The COVID-19 pandemic disrupted thousands of clinical trials involving hundreds of thousands of participants, and billions of dollars of scientific investment. Yet, until very recently there were no guidelines, frameworks or standards for clinical trials that are disrupted in extenuating circumstances (e.g. pandemic, natural disaster).

An international team of scientists, patient representatives, trial investigators, methodologists and statisticians, ethicists, funders, regulators, and journal editors convened to develop the CONSERVE (CONSORT and SPIRIT Extension for RCTs Revised in Extenuating Circumstances) Statement. CONSERVE is an extension to CONSORT and SPIRIT that guide on how to report on trials and trial protocols that face important modifications in extenuating circumstances such as the COVID-19 pandemic. CONSERVE was developed using a consensus process, a rapid review, and a survey of the international trials community.

To make CONSERVE easy to implement, the statement incorporates an implementation tool and checklists tailored to trial reports and trial protocols. The checklists include 4 sections capturing extenuating circumstances, important modifications, responsible parties, and interim data analyses. The aim is to transparently report which extenuating circumstances have led to important modifications in randomized trials and trial protocols.

The CONSERVE Statement was published in JAMA and is available at the EQUATOR Network website.

Free Course on COVID-19 and Mental Health

This two-webinar course provides learners with an opportunity to select a webinar that best meets their needs depending on their setting (hospital/healthcare facility or college/university campus). The remainder of this year will see many settings continue to return to pre-pandemic operations and the challenges and stressors these transitions present can be challenging. In both webinars, learners explore ways to work through those challenges.

Vote for the Participators!

 

The Clinical Trials Education and Awareness Committee (CTEA) would appreciate your support!  The Participators video was submitted for the Institute of Human Development, Child and Youth Health (IHDCYH) Talks 2021 Awards competition.

The public voting for the 2021 IHDCYH Talks video competition is now open until November 1, 2021.Voting makes up 10% of the ranking/rating in determining winners!


  • Click on the link provided in this email
  • Scroll down to the 13th submission (The Participators)
  • Watch the video
  • Like the video


  • Please share with your networks including colleagues, teammates, and via available social media channels


Let’s help the N2 CTEA Committee win this award. Every vote counts.